Adelaide [Australia], February 18: While many people are addicted to coffee and can't let go of the adrenaline rush it gives to the sip their favorite version- long black, espresso, or latte, a new study has revealed that too much of coffee could be detrimental for your heart health.

In a world-first genetic study, researchers from the Australian Centre for Precision Health at the University of South Australia found that that long-term, heavy coffee consumption - six or more cups a day - can increase the number of lipids (fats) in your blood to significantly heighten your risk of cardiovascular disease (CVD). Coffee Substitutes: Why Chicory Coffee is Cheaper and Healthier Than Your Regular Cup of Joe.

Importantly, this correlation is both positive and dose-dependent, meaning that the more coffee you drink, the greater the risk of CVD.

It's a bitter pill, especially for lovers of coffee, but according to UniSA researcher, Professor Elina Hypponen, it's one we must swallow if we want keep our hearts healthy.  Weight Loss Tip of the Week: How Drinking Green Coffee Helps Lose Weight (Watch Video).

"There's certainly a lot of scientific debate about the pros and cons of coffee, but while it may seem like we're going over old ground, it's essential to fully understand how one of the world's most widely consumed drinks can impact our health," said Professor Hypponen.

"In this study we looked at genetic and phenotypic associations between coffee intake and plasma lipid profiles - the cholesterols and fats in your blood - finding causal evidence that habitual coffee consumption contributes to an adverse lipid profile which can increase your risk of heart disease," added Professor Hypponen.

Professor Hypponen further noted, "High levels of blood lipids are a known risk factor for heart disease, and interestingly, as coffee beans contain a very potent cholesterol-elevating compound (cafestol), it was valuable to examine them together."

Cafestol is mainly present in unfiltered brews, such as French press, Turkish and Greek coffees, but it's also in espressos, which is the base for most barista-made coffees, including lattes and cappuccinos.

There is no or very little cafestol in filtered and instant coffee, so with respect to effects on lipids, those are good coffee choices.

"The implications of this study are potentially broad-reaching. In my opinion it is especially important for people with high cholesterol or who are worried about getting heart disease to carefully choose what type of coffee they drink," said Professor Hypponen.

Professor Hypponen added, "Importantly, the coffee-lipid association is dose-dependent - the more you drink unfiltered coffee the more it raises your blood lipids, putting you at greater risk of heart disease."

Globally, an estimated 3 billion cups of coffee are consumed every day. Cardiovascular diseases are the number one cause of death globally, taking an estimated 17.9 million lives each year.

The study used data from 362,571 UK Biobank participants, aged 37-73 years, using a triangulation of phenotypic and genetic approaches to conduct comprehensive analyses.

While the jury still may be out on the health impacts of coffee, Professor Hypponen said it is always wise to choose filtered coffee when possible and be wary of overindulging, especially when it comes to a stimulant such as coffee.

"With coffee being close to the heart for many people, it's always going to be a controversial subject," said Professor Hypponen.

"Our research shows, excess coffee is clearly not good for cardiovascular health, which certainly has implications for those already at risk. Of course, unless we know otherwise, the well-worn adage usually fares well - everything in moderation - when it comes to health, this is generally good advice," Professor Hypponen concluded.