Washington, June 13: Access to the abortion pill mifepristone will not change after the US Supreme Court unanimously rejected an effort on Thursday by anti-abortion groups to roll back its availability, a win for abortion rights supporters and millions of women in states where abortion is legal.

Despite the ruling, women's access to mifepristone still largely depends on a patchwork of state laws, with only about half of states allowing full access under the terms approved by the federal government. Here's a look at what Thursday's decision does and does not mean for abortion access. What is Mifepristone? Why Has It Been Banned By Texas Judge? Everything You Need to Know.

What did the Supreme Court decide?

Essentially, the justices said the anti-abortion doctors who brought the case did not have the legal standing to sue the Food and Drug Administration over the drug's safety or the FDA's policies in making it more widely available. The FDA approved the drug more than 20 years ago and has reiterated its safety and effectiveness.

The anti-abortion doctors, under the name the Alliance for Hippocratic Medicine, argued they might have to treat emergency room patients who experience serious injuries after taking mifepristone. They had asked the court to strike down several FDA policies that have made the drug easier to obtain, alleging the agency overlooked the drug's safety risks.

While the decision keeps mifepristone available, legal experts say that other groups or individuals who believe they can show a stronger legal connection to the drug might try to sue along similar lines. “It's a win that the status quo is preserved but it doesn't signal that these are now dead arguments that others aren't going to try and pursue,” Rachel Rebouche, a law professor at Temple University.

What is mifepristone?

Mifepristone is a prescription drug that helps end pregnancies by dilating the cervix and blocking effects of the hormone progesterone, which is needed to sustain a pregnancy. It is usually taken with a second drug, misprostol, that causes the uterus to cramp and contract. The two-drug regimen is used to end a pregnancy through 10 weeks gestation.

What does the ruling mean for the status of mifepristone?

Mifepristone remains fully approved and available under the latest FDA framework, which includes telehealth prescribing and mail delivery to patients. The FDA has also expanded availability to large pharmacy chains and allowed prescribing by nurses and other health professionals, not just physicians. Those policies have increased the prescribing of mifepristone, which accounted for nearly two-thirds of all US abortions last year.

Access to the pills is restricted across large swaths of the country because of state laws that ban abortion (including medication abortion) outright or impose separate restrictions on the drug's use. US Abortion Pill Ruling: Texas Judge Suspends FDA’s Two-Decade-Old Approval.

How do state laws impact access to mifepristone?

Access largely depends on the laws in the state where a patient lives and — in the case of states banning or restricting mifepristone — what steps they are willing to take to circumvent them. About half of US states allows online prescribing and mail delivery of mifepristone, conforming to the FDA-approved labeling for the drug.

Currently, 14 states are enforcing bans on abortion at all stages of pregnancy. Another dozen or so states have laws specifically limiting how mifepristone can be prescribed and distributed, such as requiring an in-person visit with a physician or separate counselling about the potential risks and downsides of the drug.

Those steps are not supported by major medical societies, including the American Medical Association, which have reiterated that mifepristone can be safely prescribed remotely and is highly effective for ending pregnancy.

What is mifepristone's record of safety and effectiveness?

The anti-abortion group that brought the case before the Supreme Court alleged that FDA regulators had overlooked serious safety issues when they approved the mifepristone and in subsequent actions easing prescribing. The FDA and the Biden administration filed multiple legal challenges reiterating the drug's track record.

US studies found that mifepristone resulted in a completed abortion 97.4 per cent of the time, according to the FDA label. Like all drugs, the abortion pill is not 100 per cent effective and in 2.6 per cent of cases, a surgical intervention was needed to complete the abortion. Less than 1 per cent of the time, the pregnancy continued.

In rare cases, mifepristone can cause serious complications including excessive bleeding, infections and other problems requiring emergency care. Those problems occur in far less than a fraction of 1 per cent of all patients using the drug, according to the FDA label.

How are medication abortions increasing despite restrictions?

Despite state laws targeting mifepristone, statistics show women in those states continue to receive the drug through the mail because state authorities have little visibility into deliveries handled by the US Postal Service. A survey earlier this year found about about 8,000 women a month in states that severely restrict abortion or place limits on telehealth prescribing were getting abortion pills by mail by the end of 2023, according to the Society of Family Planning.

Additionally, some patients order the drug through international pharmacies, which are outside the jurisdiction of US authorities.

What does the decision mean for other drugs and vaccines?

Drugmakers and patient groups had warned that a ruling against mifepristone could undermine the FDA's century-plus-long regulatory authority by inviting more challenges to medicines the agency has deemed safe and effective. The decision may help discourage legal challenges to other medical products that have attracted political controversy, such as vaccines, HIV treatments and emergency contraceptives.

What's next for legal challenges to mifepristone?

Legal experts say other parties could bring new lawsuits. Idaho, Kansas and Missouri sought to join the case against the FDA and the Biden administration, which Supreme Court rejected — though a conservative Texas judge who initially ruled against the FDA allowed them to join the case in his district. The three states, all led by Republican attorneys general, could try to revive the case at the lower court, arguing they have state interests in blocking mifepristone's use.

“They are not physicians who have to show that they actually have some relationship to abortion care,” said Rebouche, of Temple University “They're claiming a state interest in the regulation of medicine, so I think that's the vehicle in which you could see a lawsuit come forward.”

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