New Delhi, Jul 17: Drug firm Zydus Cadila on Friday said it has received approval from Mexico's regulatory authority Cofepris to conduct clinical trials in the Latin American country with its biological therapy "Pegylated Interferon alpha-2b" for treatment of COVID-19.

Clinical and regulatory development of the therapy in COVID-19 is being executed in Mexico by Avant Santé Research Center S.A. de C.V., a contract research organisation (CRO) headquartered in Monterrey, Mexico.

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In a regulatory filing, Zydus Cadila said it had received approval from the Mexican regulatory authority Cofepris to conduct clinical trials with its biological therapy, Pegylated Interferon alpha-2b, 'PegiHepTM'. COVID-19 Vaccine Update: Oxford Coronavirus Vaccine Early Stage Trial Shows Promise, Says Report.

It added that “this will be an open-label, randomised, comparator controlled study... to evaluate safety, efficacy and tolerability in patients with COVID-19”.

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Zydus had earlier approached the Drug Controller General of India to investigate the role of Pegylated Interferon alpha-2b for COVID-19 and the clinical trials are now underway, the company said.

It is also working with the US Food and Drug Administration to open an investigational new drug application for Pegylated Interferon alpha-2b.

Earlier this month, Zydus Cadila had also received approval from Cofepris to test one of its lead research candidate Desidustat in the management of COVID-19.

Shares of Cadila Healthcare, the listed entity of the group, were trading 1.14 per cent higher at Rs 365.05 apiece on BSE. PTI SVK ANS ANS 07171029 NNNNlent scouts in Europe, previously worked with RB Leipzig and Premier League clubs Southampton and Tottenham.

Eight-time French champion Monaco has been struggling with consistency since upsetting PSG to win the league three years ago, when it also reached the Champions League semifinals with an exciting brand of soccer which produced more than 150 goals that season.

Mitchell's immediate task is building a strong enough squad to return to the Champions League. Monaco finished a modest ninth last season, having narrowly avoided relegation the season before during a turbulent campaign where it sacked Leonardo Jardim, hired former France great Thierry Henry, then sacked Henry and re-hired Jardim.

Jardim, who guided Monaco to the 2017 league title, was then fired again last December to make way for Robert Moreno.

Moreno will be hoping to keep the 29-year-old France international Ben Yedder, who is being courted by several big clubs. French clubs resumed training this week for the new season, which is set to start on Aug. 22.

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